The electromagnetic field (EMF) has an effect on various organs, including the female reproductive system. The purpose of this study was to evaluate the impact of carnosine on ovarian follicle number and diameter in rats exposed to a 900 Megahertz (Mhz) electromagnetic field. In this study, six different groups were used. 40 female rats divided into groups were evaluated. The ovaries of the rats were removed at the end of the study. Routine histological procedures were performed on ovarian tissues. Follicle number and diameter of all groups were calculated and evaluated under the light microscope. When primary follicle number and diameters were compared statistically among the groups, there was a remarkably meaningful difference between the EMF group and the control, 20 mg carnosine and EMF+20 mg carnosine groups (p<0.05). There were significant irregularities in the structure of the oocyte and the granulosa cells surrounding the oocyte, especially in the EMF-treated groups. However, the structure of the oocyte and the granulosa cells surrounding the oocyte in the EMF+20 mg carnosine group showed a more regular structure compared to the EMF group. In this study, it can be concluded that the number and diameter of ovarian follicles decreased in rats exposed to electromagnetic field and 20 mg of carnosine may prevent damage caused by EMF.
Ayla Arslan1, Esra Balcioğlu2, Mehtap Nisari1, Betül Yalçin2, Menekşe Ülger2, Emel Güler3, Gökçe Bağcı Uzun4, Niyazi Acer5
1 Erciyes University Faculty of Medicine, Department of Anatomy, Kayseri, Turkey
2 Erciyes University Faculty of Medicine, Department of Histology and Embryology, Kayseri, Turkey
3 Cumhuriyet University Faculty of Medicine, Department of Physical Medicine and Rehabilitation. Algology, Sivas, Turkey
4 Turgut Ozal University Faculty of Medicine, Department of Anatomy, Malatya Turkey
5 Arel University Faculty of Medicine, Department of Anatomy, Istanbul, Turkey