The human cerebellum has a complex process of development. The cerebellum vermis is one of its main structures and its abnormal development has been related to different pathologies. There is still very little information about the normal measures of the cerebellum vermis during its development. Image techniques have a temporality limitation, plus they are operant dependent. The main objective of this research is to establish a nomogram of in vivo measures of human fetuses to contribute to the diagnosis of cerebellum malformations. We made an encephalic dissection of 33 human fetuses from the 14 to 21 weeks of gestation to expose the cerebellum. A dissection of the cerebellum was made to expose the cerebellum vermis, which was measured in three axes: craniocaudal, anteroposterior, and obliquus axes. Results were reported as the mean of each axis in millimeters and with the standard deviation. A Pearson´s correlation test was made between each of the axes with the gestational age.
The three measured axes showed an increasing growth pattern during the studied period. They also showed a strong correlation between these increasing measures as the gestational age increases. We described a series of measures of different axes of the cerebellum vermis. Our results help define the normal dimensions of this structure, which ultimately could ease the diagnosis of a malformation such as a cerebellum vermis hypoplasia or agenesis. Further research should be carried out to increase the validity of these results.