Eur J Anat, 24 (6): 467-473 (2020)

Corpus callosum morphology of healthy children: a structural magnetic resonance imaging study from Turkey

Mustafa E. Akin¹, Ayşegul N.Ã?. Kurt²

¹Radiology Department, Ankara Yıldırım Bayazıt University, Yenimahalle Training and Research Hospital, Ankara, Turkey²Pediatric Neurology Division, Pediatrics Department, Ankara Yıldırım Bayazıt University, Yenimahalle Training and Research Hospital, Ankara, Turkey

ABSTRACT Morphological measurement of corpus callosum (CC) in magnetic resonance imaging studies has an important value for clinical decision-making dur-ing the period of childhood. Although there is evi-dence for differences in brain morphology in terms of socioeconomic disparities, there is no research specifically on CC morphology from any low- and middle-income countries. This study aims to report structural measurements and area of CC of healthy children from Turkey, a middle-income country, and find out whether the CC morphology differs between male and female children in differ-ent age groups. Healthy children aged 6-18 years were recruited retrospectively and their CC antero-posterior (AP) length, genu, body and splenium width (GW, BW, SW) and CC midsagittal area were measured from magnetic resonance imaging studies. Independent sample t-test was used to compare CC measurements of the sex and age groups. Pearson correlation test was used to de-termine linear correlations between age and CC parameters. The sample consisted of 200 healthy children; at least 5 female and 5 male children for each age; 103 (51.5%) females, 97 (45.5%) males.

Keywords: Corpus callosum â?? Magnetic reso-nance imaging â?? Morphological and microscopic findings â?? Child â?? Age factors