TY  - JOUR
A1  - ,  
T1  - Protective efficacy of Allium jesdianum on liver parameters, inflammatory cytokines, oxidative injury and apoptotic changes in mercuric chloride-induced hepatotoxicity in rats
JO  - Eur. J. Anat.
SN  - 1136-4890
Y1  - 2020
VL  - 24
SP  - 381
EP  - 389
UR  - http://www.eurjanat.com/web/paper.php?id=200159ms
KW  - Allium Jesdianum â?? Mercuric chloride â?? Oxidative â?? Apoptosis â?? Hepatotoxicity â?? Inflammation
N2  - Mercuric chloride (MC) is a chemical compound made from a combination of mercury and chlorine causing intracellular oxidative stress generation. Allium jesdianum (AJ), as a member of the Liliace-ae family, has various pharmacological and strong antioxidant properties. This study aimed to evalu-ate the probable therapeutic effects of AJ against hepatocytes degeneration, inflammation, apoptotic changes and oxidative injuries induced by MC ad-ministration. Sixty-four rats were randomly divided in eight groups (n = 8) including groups of control, MC (50 mg/kg), AJ (500, 1000, 2000 μg/ml), and MC+AJ. They were intraperitoneally and orally ad-ministrated for one week. Nitrite oxide, lipid peroxi-dation (LP) levels, and Ferric Reducing Ability ofPlasma (FRAP) assays were conducted to evalu-ate the intracellular antioxidant index.
ER  -