TY - JOUR A1 - , T1 - Agenesis of isthmus of thyroid gland and ectopic locations of the inferior parathyroid glands and thymus JO - Eur. J. Anat. SN - 1136-4890 Y1 - 2008 VL - 12 SP - 127 EP - 132 UR - http://www.eurjanat.com/web/paper.php?id=08020127 KW - aged KW - anatomical variation KW - article KW - cadaver KW - case report KW - ectopic organ KW - ectopic thymus KW - female KW - histopathology KW - human KW - human tissue KW - mediastinum KW - neck dissection KW - parathyroid ectopia KW - thyroid dysgenesis KW - thyroid follicle N2 - The aim of this study is to report a case of agenesis of the isthmus of the thyroid gland, and ectopic locations of the inferior parathyroid glands and thymus observed in an 80-year old female cadaver during routine dissection of the head and neck. The two lobes of the thyroid gland were small and connected by pretracheal fascia at the midline, which upon histological study were seen to contain mainly connective tissue, with a few minute follicles laterally. A 2.5-cm-long portion of glandular tissue was seen posterior to the left lobe, which upon histological study proved to be an ectopic thymus with cysts. The location of the superior parathyroid glands was normal. The right inferior parathyroid gland was situated close and anteriorly to the inferior pole of the right lobe. The left inferior parathyroid gland was seen within the thymus in the superior mediastinum. Ectopic locations of the inferior parathyroid gland and the thymus have been attributed to abnormal migration during embryogenesis and common origin from the third pouch. ER -