TY  - JOUR
A1  - ,  
T1  - Immunocytochemical distribution of the AMPA receptor subunits GluR2/3 and GluR4 in the cristae ampullares of the hatched chicken
JO  - Eur. J. Anat.
SN  - 1136-4890
Y1  - 2003
VL  - 7
SP  - 79
EP  - 83
UR  - http://www.eurjanat.com/web/paper.php?id=03020079
KW  - AMPA receptor
KW  - glutamate receptor 2
KW  - glutamate receptor 3
KW  - glutamate receptor 4
KW  - peroxidase
KW  - receptor subunit
KW  - animal tissue
KW  - article
KW  - chicken
KW  - cristae ampullares
KW  - development
KW  - electron microscopy
KW  - electrophysiology
KW  - epithelium
KW  - ganglion
KW  - hair cell
KW  - hair cell type I
KW  - hair cell type II
KW  - histology
KW  - immunocytochemistry
KW  - microscopy
KW  - neurotransmission
KW  - newborn
KW  - nonhuman
KW  - preembedding immunoperoxidase method
KW  - sensory nerve
KW  - technique
KW  - tissue distribution
KW  - ultrastructure
KW  - vestibular system
KW  - vestibular system epithelium
KW  - vestibule ganglion
N2  - A preembedding immunoperoxidase method was used to study the distribution of the GluR2/3 and GluR4 AMPA subunits of the ionotropic glutamate receptors in the peripheral vestibular epithelium of the hatched chicken. At the light microscopic level, a strong immunoreactivity for both subunits was observed around type I hair cells in the cristae ampullares. At ultrastructural level, immunoreaction product was accumulated in calyx-type profiles of vestibular ganglion afferent fibres closely attached to type I hair cells. Occasionally, bouton-type endings supposedly on type II hair cells were immunostained for GluR4. These observations, together with the electrophysiological evidence, suggest that GluR2/3 and GluR4 subunits play a role in the transmission of vestibular sensory information during early development of the chicken.
ER  -