TY - JOUR A1 - , T1 - The role of growth hormone in bone response for implant treatment. Experimental study using presenile animals JO - Eur. J. Anat. SN - 1136-4890 Y1 - 2001 VL - 5 SP - 105 EP - 111 UR - http://www.eurjanat.com/web/paper.php?id=01020105 KW - growth hormone KW - titanium KW - age KW - aged KW - animal cell KW - animal experiment KW - animal model KW - animal tissue KW - article KW - bone development KW - bone maturation KW - bone plate KW - bone regeneration KW - bone tissue KW - controlled study KW - growth hormone release KW - histopathology KW - hormone action KW - implant KW - nonhuman KW - osteocyte KW - presenile dementia N2 - Many factors can modify osteointegration, among them the subject's age and the possibility of using hormone treatment to improve the phenomenon. In the present study we used a histological technique that permits study not only of interface, but also bone response in distant areas. Growth hormone (GH) was used topically in aged animals that had received a titanium plate as an implant in their tibiae. A similar degree of osteointegration was observed in both, the control and treated groups. Distantly located bone issue urderwent certain modifications in its osteocyte lacunae in the treated group but not in the control group. ER -