TY  - JOUR
A1  - ,  
T1  - Retinal glial cells in alcohol-treated chick embryos
JO  - Eur. J. Anat.
SN  - 1136-4890
Y1  - 2001
VL  - 5
SP  - 97
EP  - 103
UR  - http://www.eurjanat.com/web/paper.php?id=01020097
KW  - alcohol
KW  - alcohol oxidation
KW  - alcoholism
KW  - animal cell
KW  - animal experiment
KW  - animal model
KW  - animal tissue
KW  - article
KW  - cell damage
KW  - cell differentiation
KW  - cellular distribution
KW  - chick embryo
KW  - controlled study
KW  - electron microscopy
KW  - embryo
KW  - embryotoxicity
KW  - glia cell
KW  - microscopic anatomy
KW  - Mueller cell
KW  - myelination
KW  - nerve fiber
KW  - nerve fiber degeneration
KW  - nonhuman
KW  - optic nerve fiber
KW  - retina bipolar ganglion cell
KW  - retina cell
KW  - retina inner plexiform layer
KW  - statistical analysis
N2  - In the present study we used electron microscope techniques to analyze the effect of ethanol on the inner layers of chick embryo retinas. We show that these layers are very strongly affected by alcohol during development, with a delay in differentiation, a considerable degree of destructuring of the inner layers, accompanied by a loss of the inner prolongations of Müller cells, and the glial cells' location at the retinal inner layers (inner plexiform layer and optic nerve fiber layer) replacing these degenerated inner prolongations. We performed a count and statistical study of the axonal loss from the optic nerve fiber layer of the retinas of ethanol-treated embryos and observed a loss of total axons, mostly of myelinic axons.
ER  -