TY - JOUR A1 - , T1 - Retinal glial cells in alcohol-treated chick embryos JO - Eur. J. Anat. SN - 1136-4890 Y1 - 2001 VL - 5 SP - 97 EP - 103 UR - http://www.eurjanat.com/web/paper.php?id=01020097 KW - alcohol KW - alcohol oxidation KW - alcoholism KW - animal cell KW - animal experiment KW - animal model KW - animal tissue KW - article KW - cell damage KW - cell differentiation KW - cellular distribution KW - chick embryo KW - controlled study KW - electron microscopy KW - embryo KW - embryotoxicity KW - glia cell KW - microscopic anatomy KW - Mueller cell KW - myelination KW - nerve fiber KW - nerve fiber degeneration KW - nonhuman KW - optic nerve fiber KW - retina bipolar ganglion cell KW - retina cell KW - retina inner plexiform layer KW - statistical analysis N2 - In the present study we used electron microscope techniques to analyze the effect of ethanol on the inner layers of chick embryo retinas. We show that these layers are very strongly affected by alcohol during development, with a delay in differentiation, a considerable degree of destructuring of the inner layers, accompanied by a loss of the inner prolongations of Müller cells, and the glial cells' location at the retinal inner layers (inner plexiform layer and optic nerve fiber layer) replacing these degenerated inner prolongations. We performed a count and statistical study of the axonal loss from the optic nerve fiber layer of the retinas of ethanol-treated embryos and observed a loss of total axons, mostly of myelinic axons. ER -