Cadaver-based research plays a crucial role in orthopedic surgery by providing high anatomical fidelity for biomechanical analysis, surgical training, and the development of new techniques. Despite its importance, the global trends and research patterns of cadaveric studies in orthopedics have not been comprehensively evaluated. This study aimed to analyze global trends, research productivity, and thematic patterns in human cadaveric orthopedic research between 2000 and 2025, with particular emphasis on clinically applied anatomy and anatomy-oriented surgical research. A comprehensive search was conducted in the Web of Science Core Collection database using an expanded search strategy related to cadaveric research and orthopedic surgery. A total of 3,428 records were identified. After applying inclusion and exclusion criteria, 461 SCI-Expanded English-language articles were included in the final bibliometric analysis. Bibliometric analyses and network visualizations were performed using VOSviewer software.
The results demonstrated a significant increase in publication output over time, with a peak in recent years. The United States was the leading contributor, followed by several developed countries. Research activity was concentrated in high-impact orthopedic journals and specialized academic centers. Keyword analysis revealed that biomechanics, anterior cruciate ligament, fracture, and shoulder disorders were the most prominent research topics. Cadaver-based research in orthopedic surgery has shown a growing and multidisciplinary trend, with a strong focus on clinically relevant topics. However, global research output remains unevenly distributed. Enhancing access to cadaveric resources and strengthening research infrastructure, particularly in developing countries, may contribute to a more balanced advancement of the field.
