European Journal of Anatomy

Official Journal of The Spanish Society of Anatomy
Cover Volume 17 - Number 1
Eur J Anat, 17 (1): 18-22 (2013)

Morphological comparison of bone marrow derived mesenchymal stem cell from albino ratsand Indian chicken

S. Saravana Kumar1, Guru B. Bhuvanalakshmi2, Mangala Gowri3,Perumal Saraswathi4

1Department of Anatomy, Saveetha Dental College, Chennai, India, 2Saveetha Dental College, Chennai, India, 3Madras Veterinary College, Chennai, India, 4Saveetha Medical College, Chennai, India

ABSTRACT The bone marrow is a complex tissue containing stem cells with hematopoietic properties. These bone-marrow mesenchymal stem cells have been identified as the source of multipotent stem cells. Bone-marrow-derived mesenchymal stem cells (BM-MSCs) are also referred to as stromal progenitor cells which are self-renewing and expandable stem cells used for regenerative studies. Basically, the mesenchymal stem cell (MSC) has the unique property of plasticity and adherence. In this study we discuss the bone-marrow-MSC isolation and their cultural characterization based on plasticity, proliferation, and CD44 cell surface marker identification in Albino Rats and Indian Chicken. The results of comparative study in the two different species indicate that there are differences in the cell morphology and proliferation rate of MSC. This article provides general understanding of the cellular morphological difference of stem cells in the lower animal models, and paves the way for future research work into the selection of species.

Keywords: BM-MSCs, Isolation, Morphology, Proliferation, Characterization

European Journal of anatomy
ISSN 2340-311X (Online)