TY - JOUR A1 - , T1 - Protective efficacy of Allium jesdianum on liver parameters, inflammatory cytokines, oxidative injury and apoptotic changes in mercuric chloride-induced hepatotoxicity in rats JO - Eur. J. Anat. SN - 1136-4890 Y1 - 2020 VL - 24 SP - 381 EP - 389 UR - http://www.eurjanat.com/web/paper.php?id=200159ms KW - Allium Jesdianum Mercuric chloride Oxidative Apoptosis Hepatotoxicity Inflammation N2 - Mercuric chloride (MC) is a chemical compound made from a combination of mercury and chlorine causing intracellular oxidative stress generation. Allium jesdianum (AJ), as a member of the Liliace-ae family, has various pharmacological and strong antioxidant properties. This study aimed to evalu-ate the probable therapeutic effects of AJ against hepatocytes degeneration, inflammation, apoptotic changes and oxidative injuries induced by MC ad-ministration. Sixty-four rats were randomly divided in eight groups (n = 8) including groups of control, MC (50 mg/kg), AJ (500, 1000, 2000 μg/ml), and MC+AJ. They were intraperitoneally and orally ad-ministrated for one week. Nitrite oxide, lipid peroxi-dation (LP) levels, and Ferric Reducing Ability ofPlasma (FRAP) assays were conducted to evalu-ate the intracellular antioxidant index. ER -