TY - JOUR A1 - , T1 - Quantitative central corneal anatomy and anaesthetic eye drops effects: Comparison between 0.4% oxybuprocaine and a combination of 0.1% tetracaine and 0.4% oxybuprocaine JO - Eur. J. Anat. SN - 1136-4890 Y1 - 2005 VL - 9 SP - 89 EP - 93 UR - http://www.eurjanat.com/web/paper.php?id=05020089 KW - anesthetic agent KW - eye drops KW - oxybuprocaine KW - tetracaine KW - adult KW - anatomical variation KW - anatomy KW - article KW - cornea thickness KW - correlation coefficient KW - drug effect KW - drug instillation KW - female KW - human KW - human experiment KW - intraocular pressure KW - male KW - normal human KW - normal value KW - observer variation KW - quantitative analysis N2 - We aimed to analyse the changes in central corneal thickness values following the instillation of 0.4% oxybuprocaine eye drops and following a combination of 0.1% tetracaine and 0.4% oxybuprocaine eye drops. Orbscan pachymetry (Orbscan II Corneal Topography System; Orbscan, Inc., Salt Lake City, UT, USA) was carried out before and three minutes after the instillation of 0.4% oxybuprocaine eye drops, and before and three minutes after the instillation of a combination of 0.1% tetracaine and 0.4% oxybuprocaine eye drops in 35 healthy subjects (n=35; aged 20-30 years). After the instillation of 0.4% oxybuprocaine eye drops there was a mean increase in central corneal thickness of 25±+11 microns. After the combination of 0.1% tetracaine and 0.4% oxybuprocaine eye drops it rose to 48±20 microns. The combination of 0.1% tetracaine and 0.4% oxybuprocaine anaesthetic eye drops causes higher increases in central corneal thickness values than 0.4% oxybuprocaine eye drops. ER -