TY - JOUR A1 - , T1 - Obstruction of trabecular orifices in primary open-angle glaucoma JO - Eur. J. Anat. SN - 1136-4890 Y1 - 2002 VL - 6 SP - 75 EP - 81 UR - http://www.eurjanat.com/web/paper.php?id=02020075 KW - adult KW - aged KW - anterior eye chamber KW - aqueous humor KW - aqueous humor flow KW - article KW - clinical article KW - disease course KW - human KW - human tissue KW - intraocular pressure KW - open angle glaucoma KW - Schlemm canal KW - trabecular meshwork N2 - The morphologic and structural changes undergone by the trabecular meshwork have frequently been related to the development of primary open-angle glaucoma, which consists of a sustained increase in intraocular pressure due to the accumulation of aqueous humour in the anterior chamber of the eye. The aqueous humour leaves the anterior chamber of the eye, passing through the trabecular orifices to Schlemm's canal. Accordingly, the anatomic integrity of the trabecular meshwork is necessary to guarantee correct aqueous drainage and the maintenence of adequate intraocular pressure. In the present study, the three-dimensional morphology of glaucomatous trabecular meshworks was studied with a view to observing morphological changes possibly related to the development of primary open angle-glaucoma. ER -