TY  - JOUR
A1  - ,  
T1  - Heterogeneous distribution of cytochrome oxidase activity in the human substantia nigra pars compacta
JO  - Eur. J. Anat.
SN  - 1136-4890
Y1  - 2000
VL  - 4
SP  - 15
EP  - 18
UR  - http://www.eurjanat.com/web/paper.php?id=00010015
KW  - acetylcholinesterase
KW  - cytochrome c oxidase
KW  - article
KW  - basal ganglion
KW  - brain region
KW  - cell heterogeneity
KW  - cytoarchitecture
KW  - enzyme activity
KW  - functional anatomy
KW  - human
KW  - human tissue
KW  - microscopy
KW  - neuroanatomy
KW  - neurochemistry
KW  - substantia nigra
N2  - The activity of the enzyme cytochrome oxidase has been analyzed in the human substantia nigra at light microscope level. The distribution of this activity is relatively uniform in the substantia nigra, except in the caudomedial region of the pars compacta, where a reduction was observed. This nigral zone matched a region characterized by its relatively high content of acetylcholinesterase activity. Our results are analyzed with reference to data in the literature, showing the existence of a neuroanatomical and functional subdivision within the pars compacta. Our findings add new proof of the known neurochemical heterogeneity of the nigral complex.
ER  -